{"id":4148,"date":"2016-12-01T15:47:14","date_gmt":"2016-12-01T06:47:14","guid":{"rendered":"http:\/\/medical-engine.com\/kusuri\/?p=4148"},"modified":"2016-12-01T15:47:14","modified_gmt":"2016-12-01T06:47:14","slug":"sglt2-inhibitory-drug","status":"publish","type":"post","link":"https:\/\/medical-engine.com\/kusuri\/sglt2-inhibitory-drug\/","title":{"rendered":"SGLT2\u963b\u5bb3\u85ac\u3068\u306f\uff1f\u52b9\u679c\u3084\u526f\u4f5c\u7528\u306f\uff1f"},"content":{"rendered":"\n<!-- Quick Adsense WordPress Plugin: http:\/\/quickadsense.com\/ -->\n<div class=\"58f770253661167565e48e9072e449ed\" data-index=\"1\" style=\"float: none; margin:30px 0 30px 0; text-align:center;\">\n<div align=\"center\">\u30b9\u30dd\u30f3\u30b5\u30fc\u30c9\u30ea\u30f3\u30af<\/div><script async src=\"\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js\"><\/script>\r\n<!-- \u85ac\u540d -->\r\n<ins class=\"adsbygoogle\"\r\n     style=\"display:block\"\r\n     data-ad-client=\"ca-pub-7421917972211870\"\r\n     data-ad-slot=\"5186138549\"\r\n     data-ad-format=\"rectangle\"><\/ins>\r\n<script>\r\n(adsbygoogle = window.adsbygoogle || []).push({});\r\n<\/script>\n<\/div>\n<p><img loading=\"lazy\" class=\"aligncenter size-full wp-image-4153\" src=\"https:\/\/medical-engine.com\/kusuri\/wp-content\/uploads\/2016\/12\/30b117609212719bce155a12f6572417_s.jpg\" alt=\"\u30ab\u30d7\u30bb\u30eb\" width=\"575\" height=\"384\" srcset=\"https:\/\/medical-engine.com\/kusuri\/wp-content\/uploads\/2016\/12\/30b117609212719bce155a12f6572417_s.jpg 575w, https:\/\/medical-engine.com\/kusuri\/wp-content\/uploads\/2016\/12\/30b117609212719bce155a12f6572417_s-300x200.jpg 300w\" sizes=\"(max-width: 575px) 100vw, 575px\" \/><\/p>\n<p>\u7cd6\u5c3f\u75c5\u306e\u6cbb\u7642\u306b\u7528\u3044\u3089\u308c\u308b\u85ac\u306b\u306f\u3001\u3055\u307e\u3056\u307e\u306a\u30bf\u30a4\u30d7\u306e\u3082\u306e\u304c\u3042\u308a\u307e\u3059\u3002\u30a4\u30f3\u30b9\u30ea\u30f3\u306e\u5206\u6ccc\u3084\u4f5c\u7528\u306b\u50cd\u304d\u304b\u3051\u308b\u85ac\u304c\u591a\u3044\u3067\u3059\u304c\u3001SGLT2\u963b\u5bb3\u85ac\u306f\u3001\u305d\u308c\u3089\u3068\u306f\u9055\u3063\u305f\u4f5c\u7528\u3067\u8840\u7cd6\u5024\u3092\u4e0b\u3052\u308b\u85ac\u3067\u3059\u3002\u3053\u3053\u3067\u306f\u3001<span style=\"color: #ff0000;\"><strong>SGLT2\u963b\u5bb3\u85ac\u306f\u3001\u3069\u306e\u3088\u3046\u306a\u4f5c\u7528\u306a\u306e\u304b\uff1f\u52b9\u679c\u3084\u526f\u4f5c\u7528<\/strong><\/span>\u306b\u3064\u3044\u3066\u307e\u3068\u3081\u307e\u3059\u3002<\/p>\n<p><\/p>\n<div id=\"toc_container\" class=\"no_bullets\"><p class=\"toc_title\">\u76ee\u6b21<\/p><ul class=\"toc_list\"><li><a href=\"#SGLT2\"><span class=\"toc_number toc_depth_1\">1<\/span> SGLT2\u963b\u5bb3\u85ac\u3068\u306f<\/a><\/li><li><a href=\"#i\"><span class=\"toc_number toc_depth_1\">2<\/span> \u52b9\u679c\u306f\uff1f<\/a><\/li><li><a href=\"#i-2\"><span class=\"toc_number toc_depth_1\">3<\/span> \u526f\u4f5c\u7528\u306f\uff1f<\/a><ul><li><a href=\"#i-3\"><span class=\"toc_number toc_depth_2\">3.1<\/span> \u4f4e\u8840\u7cd6<\/a><\/li><li><a href=\"#i-4\"><span class=\"toc_number toc_depth_2\">3.2<\/span> \u5c3f\u8def\u611f\u67d3\u75c7\u30fb\u6027\u5668\u611f\u67d3\u75c7<\/a><\/li><li><a href=\"#i-5\"><span class=\"toc_number toc_depth_2\">3.3<\/span> \u8131\u6c34\u75c7\u72b6<\/a><\/li><li><a href=\"#i-6\"><span class=\"toc_number toc_depth_2\">3.4<\/span> \u30b1\u30c8\u30a2\u30b7\u30c9\u30fc\u30b7\u30b9<\/a><\/li><\/ul><\/li><li><a href=\"#i-7\"><span class=\"toc_number toc_depth_1\">4<\/span> \u307e\u3068\u3081<\/a><\/li><\/ul><\/div>\n<h2><span id=\"SGLT2\">SGLT2\u963b\u5bb3\u85ac\u3068\u306f<\/span><\/h2>\n<p>\u7cd6\u5c3f\u75c5\u306f\u3001\u7cd6\u5c3f\u75c5\u60a3\u8005\u306e\u5c3f\u306b\u7518\u307f\u304c\u3042\u308b\u3053\u3068\u304b\u3089\u3001\u305d\u306e\u75c5\u540d\u304c\u3064\u3044\u305f\u306e\u3067\u3059\u304c\u3001\u5b9f\u969b\u3001\u7cd6\u5c3f\u75c5\u3067\u306f\u3001\u814e\u81d3\u3067\u518d\u5438\u53ce\u3057\u304d\u308c\u306a\u304f\u306a\u3063\u305f\u7cd6\u304c\u5c3f\u4e2d\u306b\u6392\u6cc4\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u306f\u3001\u7d50\u679c\u7684\u306b\u9ad8\u304f\u306a\u308a\u3059\u304e\u308b\u8840\u7cd6\u3092\u6291\u3048\u308b\u3053\u3068\u306b\u3082\u306a\u308a\u307e\u3059\u3002\u3053\u306e\u73fe\u8c61\u304b\u3089\u3001\u8840\u4e2d\u306e\u7cd6\u3092\u6392\u6cc4\u3059\u308b\u3053\u3068\u306b\u3088\u3063\u3066\u8840\u7cd6\u3092\u4e0b\u3052\u3088\u3046\u3068\u958b\u767a\u3055\u308c\u305f\u306e\u304cSGLT2\u963b\u5bb3\u85ac\u3067\u3059\u3002<\/p>\n<p>\u4f53\u5185\u306b\u306f\u3001\u300c<span style=\"color: #ff0000;\">SGLT\uff08sodium dependent glucose transporter \uff1a\u30ca\u30c8\u30ea\u30a6\u30e0\u4f9d\u5b58\u6027\u30b0\u30eb\u30b3\u30fc\u30b9\u8f38\u9001\u4f53\uff09<\/span>\u300d\u3068\u547c\u3070\u308c\u308b\u305f\u3093\u3071\u304f\u8cea\u304c\u3042\u308a\u3001\u7d30\u80de\u5185\u306b\u30ca\u30c8\u30ea\u30a6\u30e0\u3092\u53d6\u308a\u8fbc\u3080\u969b\u306b\u30b0\u30eb\u30b3\u30fc\u30b9\uff08\u30d6\u30c9\u30a6\u7cd6\uff09\u3092\u4e00\u7dd2\u306b\u53d6\u308a\u8fbc\u3080\u50cd\u304d\u3092\u3057\u3066\u3044\u307e\u3059\u3002SGLT\u306f\u3001\u3055\u3089\u306bSGLT1\u3001SGLT2\u3001SGLT3\u306b\u5206\u985e\u3055\u308c\u3001\u3055\u307e\u3056\u307e\u306a\u81d3\u5668\u3084\u7d44\u7e54\u306b\u5b58\u5728\u3057\u3066\u3044\u307e\u3059\u304c\u3001\u305d\u308c\u305e\u308c\u3001\u5b58\u5728\u3059\u308b\u90e8\u4f4d\u304c\u7570\u306a\u308a\u307e\u3059\u3002<\/p>\n<p>\u3053\u306e\u3046\u3061\u3001SGLT2\u306f\u3001\u814e\u81d3\u306e\u8fd1\u4f4d\u5c3f\u7d30\u7ba1\u306e\u307f\u306b\u5b58\u5728\u3057\u3001\u5c3f\u304b\u3089\u7cd6\u306e\u518d\u5438\u53ce\u3092\u884c\u3063\u3066\u3044\u307e\u3059\u3002SGLT2\u963b\u5bb3\u85ac\u306f\u3001\u3053\u306eSGLT2\u306e\u50cd\u304d\u3092\u963b\u5bb3\u3057\u3066\u3001\u5c3f\u304b\u3089\u306e\u7cd6\u306e\u518d\u5438\u53ce\u3092\u6291\u3048\u3001\u7cd6\u306e\u5c3f\u4e2d\u3078\u306e\u6392\u6cc4\u3092\u4fc3\u3057\u3001\u8840\u7cd6\u5024\u3092\u4e0b\u3052\u307e\u3059\u3002\u4e3b\u306a\u85ac\u5264\u306b\u306f\u3001\u30a4\u30d7\u30e9\u30b0\u30ea\u30d5\u30ed\u30b8\u30f3\u3001\u30c0\u30d1\u30b0\u30ea\u30d5\u30ed\u30b8\u30f3\u3001\u30eb\u30bb\u30aa\u30b0\u30ea\u30d5\u30ed\u30b8\u30f3\u306a\u3069\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n<p>&nbsp;<\/p>\n<h2><span id=\"i\">\u52b9\u679c\u306f\uff1f<\/span><\/h2>\n<p>SGLT2\u963b\u5bb3\u85ac\u306f\u3001<span style=\"color: #ff0000;\">\u7cd6\u306e\u5c3f\u4e2d\u6392\u6cc4\u3092\u4fc3\u3059<\/span>\u305f\u3081\u3001\u4f53\u5185\u3067\u30a8\u30cd\u30eb\u30ae\u30fc\u3068\u306a\u308b\u7cd6\u304c\u6e1b\u308b\u3053\u3068\u306b\u306a\u308a\u307e\u3059\u3002\u30a8\u30cd\u30eb\u30ae\u30fc\u304c\u8db3\u308a\u306a\u304f\u306a\u308b\u3068\u5185\u81d3\u8102\u80aa\u3092\u71c3\u713c\u3057\u3066\u30a8\u30cd\u30eb\u30ae\u30fc\u3092\u4f5c\u308b\u3088\u3046\u306b\u306a\u308a\u3001\u4f53\u91cd\u306e\u6e1b\u5c11\u3084\u3001\u8840\u5727\u306e\u6539\u5584\u52b9\u679c\u3082\u3042\u308a\u3001\u80a5\u6e80\u306e\u3042\u308b\u7cd6\u5c3f\u75c5\u306b\u9069\u3057\u3066\u3044\u307e\u3059\u3002\u307e\u305f\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u306e\u5206\u6ccc\u306b\u95a2\u4e0e\u305b\u305a\u306b\u8840\u7cd6\u3092\u4e0b\u3052\u308b\u305f\u3081\u3001\u4f4e\u8840\u7cd6\u3092\u8d77\u3053\u3059\u30ea\u30b9\u30af\u304c\u5c11\u306a\u3044\u85ac\u3067\u3059\u3002<\/p>\n<p><\/p>\n<h2><span id=\"i-2\">\u526f\u4f5c\u7528\u306f\uff1f<\/span><\/h2>\n<p>\u7d9a\u3044\u3066\u3001\u526f\u4f5c\u7528\u3092\u898b\u3066\u3044\u304d\u307e\u3057\u3087\u3046\u3002<\/p>\n<h3><span id=\"i-3\">\u4f4e\u8840\u7cd6<\/span><\/h3>\n<p>SGLT2\u963b\u5bb3\u85ac\u5358\u72ec\u3067\u306f\u3001\u4f4e\u8840\u7cd6\u3092\u8d77\u3053\u3057\u306b\u304f\u3044\u3068\u8a00\u308f\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u4f4e\u8840\u7cd6\u306e\u5831\u544a\u306f\u3042\u308a\u307e\u3059\u306e\u3067\u3001\u6ce8\u610f\u304c\u5fc5\u8981\u3067\u3059\u3002\u4ed6\u306e\u8840\u7cd6\u964d\u4e0b\u85ac\u3092\u4f75\u7528\u3057\u3066\u3044\u308b\u5834\u5408\u306f\u3001\u7279\u306b\u6ce8\u610f\u3057\u307e\u3057\u3087\u3046\u3002<\/p>\n<p><span style=\"color: #ff0000;\">\u624b\u8db3\u306e\u3075\u308b\u3048\u3084\u52d5\u60b8\u3001\u51b7\u3084\u6c57\u3001\u3081\u307e\u3044\u3001\u982d\u75db\u306a\u3069<\/span>\u306e\u4f4e\u8840\u7cd6\u75c7\u72b6\u304c\u73fe\u308c\u305f\u3089\u3001\u7802\u7cd6\u3084\u7cd6\u8cea\u3092\u542b\u3080\u98df\u54c1\u3092\u6442\u308a\u307e\u3057\u3087\u3046\u3002\u305f\u3060\u3057\u3001\u03b1\u30b0\u30eb\u30b3\u30b7\u30c0\u30fc\u30bc\u963b\u5bb3\u85ac\u3092\u670d\u7528\u3057\u3066\u3044\u308b\u5834\u5408\u306f\u3001\u30d6\u30c9\u30a6\u7cd6\u3092\u6442\u53d6\u3057\u307e\u3057\u3087\u3046\u3002<\/p>\n<p>&nbsp;<\/p>\n<h3><span id=\"i-4\">\u5c3f\u8def\u611f\u67d3\u75c7\u30fb\u6027\u5668\u611f\u67d3\u75c7<\/span><\/h3>\n<p>\u5c3f\u4e2d\u306e\u7cd6\u5206\u304c\u5897\u3048\u308b\u306e\u3067\u3001\u5c3f\u8def\u611f\u67d3\u75c7\u3084\u6027\u5668\u611f\u67d3\u75c7\u3092\u8d77\u3053\u3057\u3084\u3059\u304f\u306a\u308a\u307e\u3059\u3002<span style=\"color: #ff0000;\">\u5c3f\u610f\u3092\u3082\u3088\u304a\u3057\u305f\u3089\u6211\u6162\u305b\u305a\u306b\u30c8\u30a4\u30ec\u306b\u884c\u304f\u3001\u9670\u90e8\u3092\u6e05\u6f54\u306b\u4fdd\u3064<\/span>\u3088\u3046\u306b\u52aa\u3081\u307e\u3057\u3087\u3046\u3002\u3082\u3057\u3001\u6b8b\u5c3f\u611f\u3084\u6392\u5c3f\u6642\u75db\u3001\u5c3f\u306e\u6fc1\u308a\u3001\u9670\u90e8\u306e\u304b\u3086\u307f\u306a\u3069\u304c\u751f\u3058\u305f\u3089\u3001\u76f4\u3050\u306b\u533b\u5e2b\u306b\u76f8\u8ac7\u3057\u307e\u3057\u3087\u3046\u3002<\/p>\n<p>&nbsp;<\/p>\n<h3><span id=\"i-5\">\u8131\u6c34\u75c7\u72b6<\/span><\/h3>\n<p>\u6392\u5c3f\u56de\u6570\u3084\u5c3f\u91cf\u304c\u5897\u3048\u308b\u3053\u3068\u304c\u3042\u308a\u3001\u8131\u6c34\u75c7\u72b6\u306b\u6ce8\u610f\u304c\u5fc5\u8981\u3067\u3059\u3002\u3067\u3059\u306e\u3067\u3001<span style=\"color: #ff0000;\">\u9069\u5ea6\u306a\u6c34\u5206\u88dc\u7d66<\/span>\u3092\u5fc3\u304c\u3051\u307e\u3057\u3087\u3046\u3002<\/p>\n<p>&nbsp;<\/p>\n<h3><span id=\"i-6\">\u30b1\u30c8\u30a2\u30b7\u30c9\u30fc\u30b7\u30b9<\/span><\/h3>\n<p>\u7cd6\u306e\u6392\u6cc4\u304c\u4fc3\u9032\u3055\u308c\u308b\u3053\u3068\u3067\u3001\u30a8\u30cd\u30eb\u30ae\u30fc\u3068\u306a\u308b\u7cd6\u304c\u6e1b\u308a\u307e\u3059\u3002\u305d\u306e\u305f\u3081\u3001\u30a8\u30cd\u30eb\u30ae\u30fc\u3092\u4f5c\u308b\u305f\u3081\u306b\u3001\u8102\u80aa\u9178\u306e\u4ee3\u8b1d\u304c\u6d3b\u767a\u306b\u306a\u308a<span style=\"color: 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